Month: May 2021

Supplementary MaterialsSupplemental data jciinsight-3-99791-s023

Supplementary MaterialsSupplemental data jciinsight-3-99791-s023. primary mediators of OS lung tropism and suggest pleiotropic, redundant mechanisms by which they could impact metastasis. Combination therapy research demonstrate proof concept for focusing on these tumor-lung relationships to influence metastatic disease. = …

The ceramide transport protein CERT mediates the inter-organelle transport of ceramide for the synthesis of sphingomyelin, presumably through endoplasmic reticulum (ER)-Golgi membrane contact sites

The ceramide transport protein CERT mediates the inter-organelle transport of ceramide for the synthesis of sphingomyelin, presumably through endoplasmic reticulum (ER)-Golgi membrane contact sites. S315E induced intracellular punctate structures, to which CERT and VAP were co-localized, and the …