Parham et al

Parham et al. 95% CI: 1.53C6.40). value was 0.05. All other statistical analyses were performed with SAS 9.1 (SAS Institute, Inc., Cary, NC, USA). 3. Results 3.1. The Distributions of Sociodemographic Characteristics and Thyroid Hormones between Thyroid Nodules and Non-Nodules Organizations The characteristics of the study human population are depicted in Table 1. A total of 1271 subjects (529 males, 742 females) were included in the final analyses; out of 1271, 402 subjects suffered from thyroid nodules. Individuals with thyroid nodules experienced older age, lower educational level, were more likely to be Umeclidinium bromide urban residents, were more likely to be married, smoked less and consumed more alcohol than those without nodules. In the mean time, subjects with thyroid nodules more likely loved unbalanced diet patterns, salty or light appetite, and non-iodized salt, compared with those without thyroid nodules. Additionally, compared with subjects without non-nodules, the subjects with thyroid nodules experienced higher levels of T3, Feet3, T4, FT4 Umeclidinium bromide and TPOAb, but lower levels of TSH, and TGAb (Table 2). Table 1 The distributions of sociodemographic characteristics among individuals with and without thyroid nodules. = 402)= 869)Value= 402)= 869)Value= 0.0538), respectively. A significant relationship was not found between thyroid hormones levels (including T3, Feet3, T4, Feet4 and TSH) and thyroid nodules. Table 3 Multiple linear regression * to estimate the correlation of thyroid nodules with thyroid hormones and autoantibodies among adults, respectively. ValueValue /th /thead MaleT3 (g/L) Low59 (39.60)227 (63.06)1.00 High90 (60.40)133 (36.94)1.39 (0.74, 2.62)0.3030FT3 (ng/L) Low48 (37.80)165 (56.51)1.00 High79 (62.20)127 (43.49)1.04 (0.92, 1.19)0.5147T4 (g/L) Low83 (53.21)262 (70.24)1.00 High73 (46.79)111 (29.76)2.26 (0.91, 5.60)0.0782FT4 (ng/L) Low101 (64.74)302 (80.97)1.00 Medium41 (26.28)47 (12.60)0.99 Umeclidinium bromide (0.50, 1.93)0.9589High14 (8.97)24 (6.43)0.73 (0.31, 1.75)0.4837TSH (mIU/L) Low141 (90.38)327 (87.67) Medium9 (5.77)37 (9.92)0.60 (0.27, 1.32)0.2027High6 (3.85)9 (2.41)1.29 (0.41, 4.07)0.6587TPOAb (KU/L) Low147 (94.23)353 (94.64)1.00 High9 (5.77)20 (5.36)1.38 (0.60, 3.21)0.4595TGAb (KU/L) Low153 (98.08)370 (99.20)1.00 High3 (1.92)3 (0.80)1.05 (0.09, 11.94)0.9703 FemaleT3 (g/L) Low66 (29.07)291 (61.26)1.00 High161 (70.93)184 (38.74)1.23 (0.67, 2.25)0.5005FT3 (ng/L) Low53 (26.50)247 (61.90)1.00 High147 (73.50)152 (38.10)0.86 (0.36, 2.06)0.7403T4 (g/L) Low119 (48.37)337 (67.94)1.00 High127 (51.63)159 (32.06)0.79 (0.52, 1.21)0.2791FT4 (ng/L) Low156 (63.41)412 (83.06)1.00 Medium67 (27.24)63 (12.70)1.05 (0.66, 1.67)0.8490High23 (9.35)21 (4.23)1.16 (0.59, 2.28)0.6675TSH (mIU/L) Low204 (82.93)396 (79.84)1.00 Medium30 (12.10)74 (14.92)0.80 (0.49, 1.300)0.3609High12 (4.88)26 (5.24)1.01 (0.47, 2.16)0.9784TPOAb (KU/L) Low212 (86.18)436 (87.90)1.00 High34 (13.82)60 (12.10)1.63 (0.99, 2.68)0.0538TGAb (KU/L) Low221 (89.84)481 (96.98)1.00 High25 (10.16)15 (3.02)3.13 (1.53, 6.40)0.0018 PooledT3 (g/L) Low125 (33.24)518 (62.04)1.00 High251 (66.76)317 (37.96)1.28 (0.83, 1.97)0.2706FT3 (ng/L) Low101 (30.89)412 (59.62)1.00 High226 (69.11)279 (40.38)1.00 (0.58, 1.72)0.9938T4 (g/L) Low202 (50.25)599 (68.93)1.00 High200 (49.75)270 (31.07)0.87 (0.62, 1.20)0.3867FT4 (ng/L) Low257 (63.93)714 (82.16)1.00 Medium108 (26.87)110 (12.66)1.02 (0.70, 1.50)0.9152High37 (9.20)45 (5.18)0.88 (0.53, 1.48)0.6360TSH (mIU/L) Low345 (85.82)723 (83.20)1.00 Medium39 (9.70)111 (12.77)0.74 (0.49, 1.12)0.1515High18 (4.48)35 (4.03)1.08 (0.58, 2.01)0.8148TPOAb (KU/L) Low359 (89.30)789 (90.79)1.00 High43 (10.70)80 (9.21)1.51 (0.99, 2.30)0.0581TGAb (KU/L) Low374 (93.03)851 (97.93)1.00 High28 (6.97)18 (2.07)2.86 (1.49, 5.51)0.0017 Open in a separate window * Adjustment for age, sex, place CACNLB3 of residence, smoking, alcohol drinking, salt appetite, types of salt, diet patterns. #: The level Umeclidinium bromide was divided from the hormone-OR number of each kind of hormone. T3: low: T3 1.3 g/L, high: T3 1.3 g/L; Feet3: low: Feet3 3.4 ng/L, high: Feet3 3.4 ng/L; T4: low: T4 100 g/L, high: T4 100 g/L; Feet4: low: Feet4 17 ng/L, medium: 17 Feet4 20 ng/L; high: Feet4 Umeclidinium bromide 20 ng/L; TSH: low: TSH 3.5 mIU/L, medium: 3.5 TSH 5.5 mIU/L; high: TSH 5.5 mIU/L; TPOAb: low: TPOAb 90 KU/L, high: TPOAb 90 KU/L; TGAb: low: TGAb 400 KU/L, high: TGAb 400 KU/L. Additionally, we explored the risk tendency using unrestricted cubic splines in STATA. The ORs of thyroid nodes for T3, Feet3, T4, Feet4 showed a parabola tendency, but the low interval of ORs is definitely close to 1. The risk of thyroid nodes was kept stable at different levels of TSH. Interestingly, the risk improved obviously when TGAb 400 KU/L among pooled samples and females, which was related with the results of the multivariable linear and logistic regressions. 4. Discussion With this report, the associations of thyroid autoantibodies with thyroid nodules were examined among 1271 Chinese coastal adults using different regression models. As.